This chicken is so delicious that my family asks me for it almost every day!

MAKINGS:
2 chicken breasts
1 teaspoon salt
1 teaspoon paprika
1 teaspoon oregano
1 tablespoon shoyo sauce
1 tablespoon oil
100 grams of grated mozzarella cheese
2 tablespoons breadcrumbs
1/2 teaspoon paprika or paprika
2 eggs
olive oil
.
Click on the link below and access other delicious recipes👇🏻
beacons.ai/superyummy

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Move – A 30 Day Yoga Journey | Yoga With Adriene

It’s here! It’s free. It’s fun. It’s never too late to create long term change. This program is an invitation to move better, feel better, and improve brain and body function significantly.

Learn more about the journey and sign up here!
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Movement is how we engage with life. So, how you move matters.

This program tells a story and creates opportunities for experiencing and understanding what true health really means through the lens of yoga, movement, neuroscience, and mindfulness.

Practice movement for processing, building muscle tone, releasing stress hormones, nourishing the nervous system, decreasing anxiety and boosting joy!

MOVE kicks off JANUARY 1st! (With the yoga starting on Jan 2nd!)

MOVE is here on YouTube, but includes free supplemental goodies to support you on your journey sent via EMAIL. Sign up for free to receive your instructions and free supplemental goodies that will accompany and support you on your journey.

Accountability is awesome! So invite 1-5 people to do this with you, NOW!

Get ready to nurture a new relationship with your body.

Let’s move together.
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SHOUT out to FWFG APP Members for making this 2022 Journey possible!

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Tagged:

MSC-Exos & diabetes-related cognitive impairment. | JIR

Data Sharing Statement

The current study was based on the results of relevant published studies.

Author Contributions

All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.

This review was funded by the Innovation Fund (No.CI2021A04803), Scientific research project of Guangdong Provincial Bureau of Traditional Chinese Medicine and Medicine (No.20231290), Shenzhen Pingshan District Health System Research Project (No.202232) and Natural Science Foundation of Jilin Province (No. YDZJ202301ZYTS475).

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110. Venkat P, Zacharek A, Landschoot-Ward J, et al. Exosomes derived from bone marrow mesenchymal stem cells harvested from type two diabetes rats promotes neurorestorative effects after stroke in type two diabetes rats. Exp Neurol. 2020;334:113456. doi:10.1016/j.expneurol.2020.113456

111. Garnier D, Ratcliffe E, Briand J, Cartron PF, Oliver L, Vallette FM. The activation of mesenchymal stem cells by glioblastoma microvesicles alters their exosomal secretion of miR-100-5p, miR-9-5p and let-7d-5p. Biomedicines. 2022;10(1):112.

112. Abner EL, Jicha GA, Shaw LM, Trojanowski JQ, Goetzl EJ. Plasma neuronal exosomal levels of Alzheimer’s disease biomarkers in normal aging. Ann Clin Transl Neurol. 2016;3(5):399–403. doi:10.1002/acn3.309

113. Fiandaca MS, Kapogiannis D, Mapstone M, et al. Identification of preclinical Alzheimer’s disease by a profile of pathogenic proteins in neurally derived blood exosomes: a case-control study. Alzheimers Dement. 2015;11(6):600–7 e1. doi:10.1016/j.jalz.2014.06.008

114. Goetzl EJ, Mustapic M, Kapogiannis D, et al. Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer’s disease. FASEB J. 2016;30(11):3853–3859. doi:10.1096/fj.201600756R

115. Hamlett ED, Ledreux A, Potter H, et al. Exosomal biomarkers in Down syndrome and Alzheimer’s disease. Free Radic Biol Med. 2018;114:110–121. doi:10.1016/j.freeradbiomed.2017.08.028

116. Ahmad W. Glucose enrichment impair neurotransmission and induce Abeta oligomerization that cannot be reversed by manipulating O-beta-GlcNAcylation in the C. elegans model of Alzheimer’s disease. J Nutr Biochem. 2022;108:109100. doi:10.1016/j.jnutbio.2022.109100

117. Chi H, Yao R, Sun C, et al. Blood neuroexosomal mitochondrial proteins predict Alzheimer disease in diabetes. Diabetes. 2022;71(6):1313–1323. doi:10.2337/db21-0969

118. Pietzner M, Wheeler E, Carrasco-Zanini J, et al. Synergistic insights into human health from aptamer- and antibody-based proteomic profiling. Nat Commun. 2021;12(1):6822. doi:10.1038/s41467-021-27164-0

119. Nakano M, Nagaishi K, Konari N, et al. Bone marrow-derived mesenchymal stem cells improve diabetes-induced cognitive impairment by exosome transfer into damaged neurons and astrocytes. Sci Rep. 2016;6:24805. doi:10.1038/srep24805

120. Lu XC, Zheng JY, Tang LJ, et al. MiR-133b Promotes neurite outgrowth by targeting RhoA expression. Cell Physiol Biochem. 2015;35(1):246–258. doi:10.1159/000369692

121. Ma X, Wang Y, Shi Y, et al. Exosomal miR-132-3p from mesenchymal stromal cells improves synaptic dysfunction and cognitive decline in vascular dementia. Stem Cell Res Ther. 2022;13(1):315. doi:10.1186/s13287-022-02995-w

122. Hancock ML, Preitner N, Quan J, Flanagan JG. MicroRNA-132 is enriched in developing axons, locally regulates Rasa1 mRNA, and promotes axon extension. J Neurosci. 2014;34(1):66–78. doi:10.1523/JNEUROSCI.3371-13.2014

123. Pan Q, Kuang X, Cai S, et al. miR-132-3p priming enhances the effects of mesenchymal stromal cell-derived exosomes on ameliorating brain ischemic injury. Stem Cell Res Ther. 2020;11(1):260. doi:10.1186/s13287-020-01761-0

124. Malcangio M. Role of the immune system in neuropathic pain. Scand J Pain. 2019;20(1):33–37. doi:10.1515/sjpain-2019-0138

125. Lang HL, Zhao YZ, Xiao RJ, et al. Small extracellular vesicles secreted by induced pluripotent stem cell-derived mesenchymal stem cells improve postoperative cognitive dysfunction in mice with diabetes. Neural Regen Res. 2023;18(3):609–617. doi:10.4103/1673-5374.350205

126. Liu S, Fan M, Xu JX, et al. Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology. J Neuroinflammation. 2022;19(1):35. doi:10.1186/s12974-022-02393-2

127. Yin F, Liu Z, Zhang D, Shen Z, Niu Z, Guo L. Identification of key genes involved in neural regeneration and the repairing effect of BDNF-overexpressed BMSCs on spinal cord ischemia-reperfusion injury in rats. Biomed Pharmacother. 2023;160:114293. doi:10.1016/j.biopha.2023.114293

128. Ma W, Wei X, Gu H, et al. Intra-amniotic transplantation of brain-derived neurotrophic factor-modified mesenchymal stem cells treatment for rat fetuses with spina bifida aperta. Stem Cell Res Ther. 2022;13(1):413. doi:10.1186/s13287-022-03105-6

129. Yu X, Qi Y, Zhao T, et al. NGF increases FGF2 expression and promotes endothelial cell migration and tube formation through PI3K/Akt and ERK/MAPK pathways in human chondrocytes. Osteoarthritis Cartilage. 2019;27(3):526–534. doi:10.1016/j.joca.2018.12.007

130. Li R, Li Y, Wu Y, et al. Heparin-poloxamer thermosensitive hydrogel loaded with bFGF and NGF enhances peripheral nerve regeneration in diabetic rats. Biomaterials. 2018;168:24–37. doi:10.1016/j.biomaterials.2018.03.044

131. Kellar D, Craft S. Brain insulin resistance in Alzheimer’s disease and related disorders: mechanisms and therapeutic approaches. Lancet Neurol. 2020;19(9):758–766. doi:10.1016/S1474-4422(20)30231-3

132. Kullmann S, Heni M, Hallschmid M, Fritsche A, Preissl H, Haring HU. Brain insulin resistance at the crossroads of metabolic and cognitive disorders in humans. Physiol Rev. 2016;96(4):1169–1209. doi:10.1152/physrev.00032.2015

133. Liyanagamage D, Martinus RD. Role of mitochondrial stress protein HSP60 in diabetes-induced neuroinflammatIon. Mediators Inflamm. 2020;2020:8073516. doi:10.1155/2020/8073516

134. Lee YS, Olefsky J. Chronic tissue inflammation and metabolic disease. Genes Dev. 2021;35(5–6):307–328. doi:10.1101/gad.346312.120

135. Cui GH, Guo HD, Li H, et al. RVG-modified exosomes derived from mesenchymal stem cells rescue memory deficits by regulating inflammatory responses in a mouse model of Alzheimer’s disease. Immun Ageing. 2019;16:10. doi:10.1186/s12979-019-0150-2

136. Kubota K, Nakano M, Kobayashi E, et al. An enriched environment prevents diabetes-induced cognitive impairment in rats by enhancing exosomal miR-146a secretion from endogenous bone marrow-derived mesenchymal stem cells. PLoS One. 2018;13(9):e0204252. doi:10.1371/journal.pone.0204252

137. Duan S, Wang F, Cao J, Wang C. Exosomes derived from MicroRNA-146a-5p-enriched bone marrow mesenchymal stem cells alleviate intracerebral hemorrhage by inhibiting neuronal apoptosis and microglial M1 polarization. Drug Des Devel Ther. 2020;14:3143–3158. doi:10.2147/DDDT.S255828

138. Nakano M, Kubota K, Kobayashi E, et al. Bone marrow-derived mesenchymal stem cells improve cognitive impairment in an Alzheimer’s disease model by increasing the expression of microRNA-146a in hippocampus. Sci Rep. 2020;10(1):10772. doi:10.1038/s41598-020-67460-1

139. Yin Z, Han Z, Hu T, et al. Neuron-derived exosomes with high miR-21-5p expression promoted polarization of M1 microglia in culture. Brain Behav Immun. 2020;83:270–282. doi:10.1016/j.bbi.2019.11.004

140. Pandey N, Rastogi M, Singh SK. Chandipura virus dysregulates the expression of hsa-miR-21-5p to activate NF-kappaB in human microglial cells. J Biomed Sci. 2021;28(1):52. doi:10.1186/s12929-021-00748-0

141. Ge X, Huang S, Gao H, et al. miR-21-5p alleviates leakage of injured brain microvascular endothelial barrier in vitro through suppressing inflammation and apoptosis. Brain Res. 2016;1650:31–40. doi:10.1016/j.brainres.2016.07.015

142. Ouyang Y, Li D, Wang H, et al. MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats. Aging Cell. 2019;18(6):e13022. doi:10.1111/acel.13022

143. Gao X, Xiong Y, Li Q, et al. Extracellular vesicle-mediated transfer of miR-21-5p from mesenchymal stromal cells to neurons alleviates early brain injury to improve cognitive function via the PTEN/Akt pathway after subarachnoid hemorrhage. Cell Death Dis. 2020;11(5):363. doi:10.1038/s41419-020-2530-0

144. Pan Q, Wang Y, Lan Q, et al. Exosomes derived from mesenchymal stem cells ameliorate hypoxia/reoxygenation-injured ECs via transferring MicroRNA-126. Stem Cells Int. 2019;2019:2831756. doi:10.1155/2019/2831756

145. Wang X, Zhou Y, Gao Q, et al. The role of exosomal microRNAs and oxidative stress in neurodegenerative diseases. Oxid Med Cell Longev. 2020;2020:3232869. doi:10.1155/2020/3232869

146. Chen P, Chen F, Lei J, Li Q, Zhou B. Activation of the miR-34a-mediated SIRT1/mTOR signaling pathway by urolithin A attenuates D-galactose-induced brain aging in mice. Neurotherapeutics. 2019;16(4):1269–1282. doi:10.1007/s13311-019-00753-0

147. Thal DR, Walter J, Saido TC, Fandrich M. Neuropathology and biochemistry of Abeta and its aggregates in Alzheimer’s disease. Acta Neuropathol. 2015;129(2):167–182. doi:10.1007/s00401-014-1375-y

148. Hur JY. gamma-Secretase in Alzheimer’s disease. Exp Mol Med. 2022;54(4):433–446. doi:10.1038/s12276-022-00754-8

149. Sun Y, Ma C, Sun H, et al. Metabolism: a novel shared link between diabetes mellitus and Alzheimer’s disease. J Diabetes Res. 2020;2020:4981814. doi:10.1155/2020/4981814

150. Chen Z, Zhong C. Decoding Alzheimer’s disease from perturbed cerebral glucose metabolism: implications for diagnostic and therapeutic strategies. Prog Neurobiol. 2013;108:21–43. doi:10.1016/j.pneurobio.2013.06.004

151. Stukas S, Robert J, Wellington CL. High-density lipoproteins and cerebrovascular integrity in Alzheimer’s disease. Cell Metab. 2014;19(4):574–591. doi:10.1016/j.cmet.2014.01.003

152. Dutta BJ, Singh S, Seksaria S, Das Gupta G, Singh A. Inside the diabetic brain: insulin resistance and molecular mechanism associated with cognitive impairment and its possible therapeutic strategies. Pharmacol Res. 2022;182:106358. doi:10.1016/j.phrs.2022.106358

153. Lee M, Ban JJ, Yang S, Im W, Kim M. The exosome of adipose-derived stem cells reduces beta-amyloid pathology and apoptosis of neuronal cells derived from the transgenic mouse model of Alzheimer’s disease. Brain Res. 2018;1691:87–93. doi:10.1016/j.brainres.2018.03.034

154. Jahangard Y, Monfared H, Moradi A, Zare M, Mirnajafi-Zadeh J, Mowla SJ. Therapeutic effects of transplanted exosomes containing miR-29b to a rat model of Alzheimer’s disease. Front Neurosci. 2020;14:564. doi:10.3389/fnins.2020.00564

155. Zhang J, Buller BA, Zhang ZG, et al. Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system. Exp Neurol. 2022;347:113895. doi:10.1016/j.expneurol.2021.113895

156. Reza-Zaldivar EE, Hernandez-Sapiens MA, Gutierrez-Mercado YK, et al. Mesenchymal stem cell-derived exosomes promote neurogenesis and cognitive function recovery in a mouse model of Alzheimer’s disease. Neural Regen Res. 2019;14(9):1626–1634. doi:10.4103/1673-5374.255978

157. Wang H, Liu Y, Li J, et al. Tail-vein injection of MSC-derived small extracellular vesicles facilitates the restoration of hippocampal neuronal morphology and function in APP/PS1 mice. Cell Death Discov. 2021;7(1):230. doi:10.1038/s41420-021-00620-y

158. Parsi S, Smith PY, Goupil C, Dorval V, Hebert SS. Preclinical evaluation of miR-15/107 family members as multifactorial drug targets for Alzheimer’s disease. Mol Ther Nucleic Acids. 2015;4(10):e256. doi:10.1038/mtna.2015.33

159. Hebert SS, Horre K, Nicolai L, et al. Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer’s disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci U S A. 2008;105(17):6415–6420. doi:10.1073/pnas.0710263105

160. Wang WX, Rajeev BW, Stromberg AJ, et al. The expression of microRNA miR-107 decreases early in Alzheimer’s disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci. 2008;28(5):1213–1223. doi:10.1523/JNEUROSCI.5065-07.2008

161. Zhang X, Huang X, Fang C, et al. miR-124 regulates the expression of BACE1 in the hippocampus under chronic cerebral hypoperfusion. Mol Neurobiol. 2017;54(4):2498–2506. doi:10.1007/s12035-016-9845-y

162. Yuyama K, Sun H, Mitsutake S, Igarashi Y. Sphingolipid-modulated exosome secretion promotes clearance of amyloid-beta by microglia. J Biol Chem. 2012;287(14):10977–10989. doi:10.1074/jbc.M111.324616

163. Yuyama K, Sun H, Sakai S, et al. Decreased amyloid-beta pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice. J Biol Chem. 2014;289(35):24488–24498. doi:10.1074/jbc.M114.577213

164. Yuyama K, Sun H, Igarashi Y, et al. Immuno-digital invasive cleavage assay for analyzing Alzheimer’s amyloid ss-bound extracellular vesicles. Alzheimers Res Ther. 2022;14(1):140. doi:10.1186/s13195-022-01073-w

165. An K, Klyubin I, Kim Y, et al. Exosomes neutralize synaptic-plasticity-disrupting activity of Abeta assemblies in vivo. Mol Brain. 2013;6:47. doi:10.1186/1756-6606-6-47

166. Perez-Gonzalez R, Kim Y, Miller C, Pacheco-Quinto J, Eckman EA, Levy E. Extracellular vesicles: where the amyloid precursor protein carboxyl-terminal fragments accumulate and amyloid-beta oligomerizes. FASEB J. 2020;34(9):12922–12931. doi:10.1096/fj.202000823R

167. Dinkins MB, Dasgupta S, Wang G, Zhu G, Bieberich E. Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer’s disease. Neurobiol Aging. 2014;35(8):1792–1800. doi:10.1016/j.neurobiolaging.2014.02.012

168. Dinkins MB, Wang G, Bieberich E. Sphingolipid-enriched extracellular vesicles and Alzheimer’s disease: a decade of research. J Alzheimers Dis. 2017;60(3):757–768. doi:10.3233/JAD-160567

Global minerals leaders to attend the Future Minerals Forum

Over 200 speakers, including CEOs from major mineral companies, are set to attend the third edition of the Future Minerals Forum, which is scheduled to take place from 9-11 January 2024 in Riyadh, Saudi Arabia.

The event features speakers from various companies, including Glencore CEO Gary Nagle, Vale CEO Eduardo Bartolomeo, Codelco Chairman Máximo Pacheco, Vale Base Metals Chairman Mark Cutifani, BlackRock’s Evy Hambro, Teck CEO Jonathan Price, and Boliden CEO Mikael Staffas.

The Future Minerals Forum will also feature speakers from various mining companies, including Ivanhoe Mines Founder and Executive Co-Chairman Robert Friedland, Barrick Gold CEO Mark Bristow, KAZ Minerals CEO Andrew Southam, and The Mosaic Company President and CEO Joc O’Rourke. These speakers will discuss investments in South Africa, the Democratic Republic of Congo, gold and copper production, and the role of corporations like Ivanhoe Mines, Barrick Gold, KAZ Minerals, and The Mosaic Company in the global mining industry.

“FMF, a government-led initiative, serves as a vital platform for fostering partnerships and dialogue among global investors, mining firms, and stakeholders. With a focus on the super region covering Africa, Western and Central Asia, FMF amplifies the voices of mineral suppliers, facilitating their pivotal role in the global green transition. In doing so, FMF supports economic development by uniting decision makers, driving investment, and promoting responsible mining, processing and manufacturing industries needed for supplying clean energy and goods.” Vice-Minister of Industry and Mineral Resources for Mining Affairs, Eng. Khalid Al-Mudaifer said.

The third edition of the program aims to develop a global critical minerals strategy, enable investments in the super region, build excellence centres, develop sustainability standards, and create a green metals hub using modern technologies and processing centres, thereby enhancing human capacities and maintaining trust with society.

The post Global minerals leaders to attend the Future Minerals Forum first appeared on Australian Resources.

Guatemala protests intensify, demanding prosecutor resignations

GUATEMALA CITY – Tens of thousands of Guatemalans marched peacefully on Thursday for the fourth consecutive day, demanding the resignation of powerful senior prosecutors accused of working to undermine President-elect Bernardo Arevalo’s ability to take office.

The center-left Arevalo was elected in a landslide win in August, but since then Attorney General Consuelo Porras has intensified efforts to disqualify his anti-graft Movimiento Semilla party and ordered raids on the electoral authority’s offices, seizing ballots.

“We’re going to paralyze the country indefinitely. We demand the resignation of the prosecutor, Consuelo Porras,” said protester Luis Pacheco, head of 48 Cantones, a large Indigenous organization.

Pacheco spoke outside Porras’ offices in Guatemala City, where other groups have been camping out since Monday, waving Guatemalan flags and hoisting signs demanding an end to corruption.

Another sign read: “Get out coup plotters.”

The prosecutor’s office has defended what it describes as lawful actions to investigate Semilla over alleged registration issues and the need to secure evidence via raids.

Arevalo, a previously little-known lawmaker who struck a cord with his campaign pledge to tackle corruption, is fighting a bitter post-election battle with entrenched foes ahead of January’s scheduled inauguration.

After he secured unexpectedly strong support in June’s first-round vote, Porras asked a judge to disqualify Semilla, alleging the six-year-old registration flaws.

Her office’s raids have prompted international criticism while also stoking popular anger. A wide range of protesters, including Indigenous people, rural farmers, and teacher and student groups have taken to the streets to demand the resignations of Porras and one of her top prosecutors, Rafael Curruchiche.

Both have been accused of corruption by the U.S. government.

President Alejandro Giammattei, who in August promised an orderly transition, nominated Porras to her present term as attorney general, and has mostly remained silent on the investigations and raids.

On Wednesday, Giammattei’s government said it was restarting transition talks with Arevalo’s team. REUTERS

Natrona County Circuit Court arraignments (10/4/23–10/5/23)

CASPER, Wyo. — Provided below are the defendants and charges from appearances in Natrona County Circuit Court on Wednesday and Thursday, Oct. 4–5.

The Honorable Seventh Judicial Circuit Court Judge Brian Christensen presided while Assistant District Attorney Blaine Nelson represented the state.

All persons entering not guilty pleas or charged with felonies are presumed innocent until convicted or pleading guilty. Official charges are subject to change by the Natrona County District Attorney’s Office.

Pleas on felony charges are not entered in circuit court, though bond conditions are set.

A bail bondsman can post a surety bond, typically requiring 10–15%.

A “personal recognizance” or “signature” bond means there is no money required to get out, but the defendant could owe the full amount if they fail to appear.

Factors affecting bond and sentencing include the nature of the crime, the weight of the evidence, the defendant’s criminal history and their ties to the community.

The standard of evidence differs in probation revocations. The state is only required to prove the allegations in an affidavit for revocation “to a preponderance of the evidence.” 

The defendant can admit and have the underlying sentenced imposed or resuspended. The defendant can also deny and seek representation at a contested hearing, and a new bond is set.

For purposes of this document, admissions and denials are represented as guilty and not guilty pleas, respectively. 

Standard fees typically include $150 to the Crime Victims Compensation Fund, $70 in court costs and $50 to Drug Court assessment. Additional fines may be imposed at sentencing. 

Felonies and engrossed misdemeanors (pleas not entered in circuit court)

  • Richard Conner, 52 – Aggravated assault and battery, aggravated burglary with a deadly weapon, unlawful entry to commit battery, stalking, violation of protection order, telephone harassment
    • $50,000 cash only
  • Kyle Pacheco, 33 – Property destruction: over $1,000, domestic battery, interference
    • $3,000 cash or surety bond
  • James Johnson, 56 – Failure to register as a sex offender
    • $5,000 cash or surety bond
  • Mason Cureton, 22 – Possession of methamphetamine, possession of marijuana, possession of clonazepam: third or subsequent upon conviction x3
    • $25,000 cash or surety bond
  • William Hamilton, 39 – Possession of methamphetamine: felony weight, possession of marijuana, DUI: controlled substance
    • $7,500 cash only
  • Tevin Sexton Marquis Taylor, 33 – Possession of methamphetamine: felony weight, interference, possession of fentanyl, possession of marijuana
    • $20,000 cash or surety bond

No contest and guilty pleas

  • Zachary Allen, 34 – Possession of a controlled substance, use of a controlled substance
    • Pleaded no contest to use of controlled substance charge
    • 30 days jail, remaining one year suspended
    • One year supervised probation
  • Clayton Cogdill, 32 – Possession of cocaine, possession of mushrooms
    • One year suspended
    • One year supervised probation
    • $600 fine
  • Nicole Greenleaf, 54 – Possession of methamphetamine, driving under suspension
    • Five days jail, remaining one year suspended
    • One year supervised probation
  • Matthew Riverkamp, 27 – Possession of methamphetamine, use of methamphetamine
    • 18 months suspended
    • Six months supervised probation
  • Alicia Smith, 23 – Domestic battery
    • Six months suspended
    • Six months unsupervised probation
    • $250 fine

Not guilty pleas

  • Joseph Peters, 37 – DUI
    • $2,000 cash or surety bond
  • Arnaldo Perez Fonseca, 32 – Fail to appear for hearing on interference charge
    • $1,000 cash or surety bond
  • Rae Cobert, 20 – Possession of methamphetamine, possession of marijuana, possession of Klonopin
    • $20,000 cash or surety bond
  • Shaun Michael Kiser, 37 – Driving under suspension, no insurance, open container in a moving vehicle, theft, no registration, possession of a controlled substance: fentanyl
    • $10,000 cash or surety bond
  • Rachel Lippett, 35 – Possession of a controlled substance, open container
    • $885 cash or surety bond continued

SU introduces Vmock, an AI-powered platform, to review student resumes

Beginning this academic year, the College of Arts and Sciences Office of Undergraduate Academic and Career Advising at Syracuse University debuted an initiative using the artificial intelligence software VMock, an online resume review software.

Though VMock has been available to all SU undergraduate students since 2020, this new initiative allows sophomores to choose between using VMock or meeting one-on-one with a career counselor to develop their resume. This initiative only extends to second-year undergraduate students with declared majors in Arts and Sciences or the Maxwell School of Citizenship and Public Affairs, though VMock is a tool available to students in other SU schools and colleges.

SU is not alone in its implementation of VMock as a step in the career advising process. Over 250 higher education institutions in more than 130 countries use VMock’s services, according to its website.

“VMock is intended as a potential, non-required, avenue and tool for all undergraduates as a first pass at their resume,” Steven Schaffling, assistant dean of student success of Arts and Sciences, told The Daily Orange in an email statement.

Sophomore students who have not already met with a career advisor are required to either schedule a 30-minute meeting or upload their resumes to VMock to lift a hold on their MySlice account, which stops students from registering for classes next semester.

If students choose a one-on-one conference, they are still instructed to upload their resumes to VMock prior to the meeting, according to an email sent to Arts and Sciences sophomore students with account holds. The email states that the VMock option takes five minutes.

Sophomores were selected to ensure that students have some version of a resume early on in their academic career, Schaffling wrote. He wrote that the Arts and Science advising office believes starting sophomore year assures that students won’t fall behind in searching for internships or other experiential education opportunities.

“In a post-pandemic age we want to be dynamic and responsive to student needs … allowing fall semester sophomores multiple avenues is the college being responsive to student needs and experience,” Schaffling wrote.

Using VMock, students can receive rapidly-generated, specific feedback, ranging from spell-check to structural issues, by uploading their resume to the VMock website or app.

Hamid Ekbia, a university professor in Maxwell and the director of SU’s Autonomous Systems Policy Institute, said it’s important to keep up human discretion with AI processes like VMock.

“That’s very encouraging to know that the entities, they try to help students, but these are statistical machines and ultimately they find patterns, and patterns are aggregate patterns, they are not individual,” Ekbia said. “As best as we might try to craft a resume that is unique to us, a lot of that might get lost in the process.”

Ekbia is teaching SU’s first AI and Humanity course this fall, listed between the School of Information Studies and Maxwell.

Though VMock’s feedback is unlimited on each resume submission, students can only upload their resumes 10 times per year, according to the SU career services website. VMock also offers community insights about resumes previously uploaded by Syracuse students, from the average number of words to the typical layout.

VMock also includes an option to start a resume from scratch by using community templates from SU’s career services. With formatting pre-determined in the templates, students only have to input their information and experience.

Resumes submitted through VMock are scored based on three categories — impact, presentation and competencies — and receive a score out of 100 points. Impact is worth up to 40 points, while presentation and competencies are both worth up to 30.

Ekbia said filtering software used in hiring practices is designed to find candidates that have similar traits and experiences to what the company is searching for, not what distinguishes candidates. Softwares like VMock can amplify this, which students need to be careful of, he said.

“What matters most when you apply for a job is what makes you different and unique, not what makes you similar to other people,” Ekbia said. “That is the biggest concern that I have with the use of these systems, because they essentially pigeonhole you.”

SU’s College of Engineering and Computer Science has also implemented VMock as part of its career advising process.

ECS Career Services regularly connects with employers to ensure the resume templates used in VMock match up with the industry standards for what a student is pursuing, Sarah Mack, the director of student success and career services for the ECS, wrote in a statement to The Daily Orange.

Dan Pacheco, a professor of practice of magazine, news and digital journalism and the Peter A. Horvitz Endowed Chair in Journalism Innovation at the S.I. Newhouse School of Public Communications, said students’ exposure to and familiarity with programs like VMock is a great way to prepare them to be successful in their job and interview searches.

Although he said services like VMock can be “foresightful,” Pacheco said it’s still important to be aware of artificial intelligence’s inherent flaws. Because artificial intelligence is created by humans — who all have their own biases — and is trained on human data, all AI software also has biases, Pacheco said.

“In the United States, that means that cis, white, heterosexual males have an even bigger advantage when applying for the best jobs because they are already in the majority in the white-collar workforce,” Pacheco wrote in a statement to The Daily Orange.

Both Schaffling and Mack shared the view that VMock is capable of addressing the different resume formats dependent upon a student’s post-graduation goals.

“Advisors and VMock both have the ability to help students put their resume into effective templates to increase their success,” Schaffling wrote.

Mack also wrote that students in the beginning stages of resume creation can use VMock so their individual meetings with advisors are more productive. If VMock has already reviewed the resume, students can focus on discussing how to gain additional experience and receive coaching on their job search when they meet with advisors, she told The D.O.

Even though AI usage can present concerns, Pacheco remains optimistic that when used correctly, the opportunities software like VMock can benefit students.

“As long as humans are using the tools in conjunction with keeping themselves in the equation, and they’re using the tools as a way to enhance what they’re able to do or make themselves more efficient, then we all need to be doing more of that,” Pacheco said.

The post SU introduces Vmock, an AI-powered platform, to review student resumes appeared first on The Daily Orange.

‘Get out, coup plotters’: Guatemala protests intensify | PerthNow

Tens of thousands of Guatemalans have marched peacefully for the fourth consecutive day, demanding the resignation of powerful senior prosecutors accused of working to undermine President-elect Bernardo Arevalo’s ability to take office.

The centre-left Arevalo was elected in a landslide win in August, but since then Attorney-General Consuelo Porras has intensified efforts to disqualify his anti-graft Movimiento Semilla party and ordered raids on the electoral authority’s offices, seizing ballots.

“We’re going to paralyse the country indefinitely. We demand the resignation of the prosecutor, Consuelo Porras,” said protester Luis Pacheco, head of 48 Cantones, a large Indigenous organisation.

Pacheco spoke on Thursday outside Porras’ offices in Guatemala City, where other groups have been camping out since Monday, waving Guatemalan flags and hoisting signs demanding an end to corruption.

Another sign read: “Get out, coup plotters.”

The prosecutor’s office has defended what it describes as lawful actions to investigate Semilla over alleged registration issues and the need to secure evidence via raids.

Arevalo, a previously little-known lawmaker who struck a cord with his campaign pledge to tackle corruption, is fighting a bitter post-election battle with entrenched foes ahead of January’s scheduled inauguration.

After he secured unexpectedly strong support in June’s first-round vote, Porras asked a judge to disqualify Semilla, alleging the six-year-old registration flaws.

Her office’s raids have prompted international criticism while also stoking popular anger. A wide range of protesters, including Indigenous people, rural farmers, and teacher and student groups have taken to the streets to demand the resignations of Porras and one of her top prosecutors, Rafael Curruchiche.

Both have been accused of corruption by the US government.

President Alejandro Giammattei, who in August promised an orderly transition, nominated Porras to her present term as attorney general, and has mostly remained silent on the investigations and raids.

On Wednesday, Giammattei’s government said it was restarting transition talks with Arevalo’s team.

Cardinal Sport Preview: Rockets Set To Open Road Portion of 2023-24 Schedule in Prince George

Kelowna Rockets at Prince George Cougars

Date | Time  Tues., Oct. 3, 2023 | 7:00 pm
Video Stream CHL TV
Radio  104.7 The Lizard + Rocket Fan App
Live Stats WHL Box Score
Live Updates @Kelowna_Rockets on X (formally Twitter)

 

Kelowna Rockets at Prince George Cougars

Date | Time  Wed., Oct. 4, 2023 | 7:00 pm
Video Stream CHL TV
Radio  104.7 The Lizard + Rocket Fan App
Live Stats WHL Box Score
Live Updates @Kelowna_Rockets on X (formally Twitter)

 

The Rockets will hit the road for the first time this regular season, heading to Prince George for a pair of games against the Cougars. Puck drop is set for 7:00 pm both Tuesday and Wednesday night at the CN Centre.

With a full lineup, the Rockets picked up their first win of the season on Saturday night with a 5-3 victory over the Wenatchee Wild. Andrew Cristall recorded a three-point (1G, 2A) night in his return from the Washington Capitals camp, while Hiroki Gojsic recorded his first two points (1G, 1A) in the WHL. Goaltender Jari Kykkanen made 26 saves on 29 shots.

The Prince George Cougars lead the league in goals scored with 29 through four games. Over the weekend the Cougars took down the Victoria Royals 11-2 on Friday and 5-3 on Saturday on the island.

Following Wednesday’s game in Prince George, the Rockets will return home to Prospera Place for a busy weekend in Kelowna. Michael Cicek’s former team, the Spokane Chiefs, will visit on Saturday, the Victoria Royals will then roll in for a 12:35 pm Thanksgiving Monday matchup that features $10 childrens tickets. Tickets for all Rockets home games can be purchased at selectyourtickets.com.


ROCKETS ROSTER UPDATES

The Rockets will be without defenceman Caden Price who is out one-to-two weeks with a lower-body injury and forward Marcus Pacheco who is out two-to-three weeks with a lower-body injury. The Rockets injury report is updated weekly and can be viewed here.

WHERE IS CAPTAIN GABBY?

As a 20-year-old import player, Gabriel Szturc has a few options of where he can play this season. He could play professionally in Europe or sign in the American Hockey League, he could also be assigned to Kelowna to spend his overage season with the Rockets.

Szturc was invited as an undrafted free agent to play for the Tampa Bay Lightning in their rookie tournament. He made his pre-season debut with the Lightning on September 27, recording 10:59 of ice time against the Nashville Predators. On September 30, Szturc was assigned to the Lightning’s AHL affiliate the Syracuse Crunch, he’s there on a try-out.


ROCKETS TO WATCH

COUGARS TO WATCH


WATCH AND LISTEN

Radio broadcast

Rockets games will be broadcast on 104.7 FM the Lizard this season with Regan Bartel calling all of the action.

Don’t forget to download the RocketFAN app and visit  for more exclusive Rockets content from Pattison. Fans can stream the radio broadcast of all Rockets games on the app.

Click here to download RocketFAN on Google Play

Click here to download RocketFAN on the App Store

Online video stream

All Rockets games will be available on WHL Live.  WHL Live on is available to fans anywhere in the world, providing high-quality streaming of WHL games on Apple TV, Roku, and Amazon Fire TV platforms, via mobile with iOS and Android, and on web using Safari or Google Chrome web browsers. Visit  for complete details and subscription options.


Six and twelve game Mini Packs for the Kelowna Rockets season are now on sale through Select Your Tickets. To learn how to save on walk-up tickets and use the flexibility of a Mini Pack click here

VIDA JUSTA / CASAS PARA VIVER – MANIFESTAÇÃO (PORTO, 30 DE SETEMBRO DE 2023) – EPHEMERA – Biblioteca e arquivo de José Pacheco Pereira

“The two offices of memory are collection and distribution.” (Samuel Johnson)

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